For women taking lithium for the treatment of bipolar disorder, choosing whether to maintain or discontinue lithium during pregnancy is challenging. This is a process which requires careful and thoughtful consideration, weighing the risk of adverse outcomes associated with exposure to lithium against the risk of recurrent illness in the setting of medication discontinuation. While we have considerable information regarding the teratogenicity of lithium, we have much less data regarding other pregnancy and neonatal outcomes.
Analyzing data from five linked Swedish national registersHastie and colleagues investigated the associations between lithium use during pregnancy and adverse pregnancy and